Myc linked to dysregulation of cholesterol transport and storage in nonsmall cell lung cancer

Myc linked to dysregulation of cholesterol transport and storage in nonsmall cell lung cancer

Nonsmall cell lung cancer (NSCLC) is a leading cause of cancer-related deaths. While mutations in Kras and overexpression of Myc are commonly found in patients, the role of altered lipid metabolism in lung cancer and its interplay with oncogenic Myc is poorly understood. Here we use a transgenic mou...

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Bibliographic Details
Main Authors: Zoe Hall, Catherine H. Wilson, Deborah L. Burkhart, Tom Ashmore, Gerard I. Evan, Julian L. Griffin
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Journal of Lipid Research
Subjects:
cholesteryl ester
liquid extraction surface analysis
mass spectrometry
lipid metabolism
adenocarcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520437277

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http://www.sciencedirect.com/science/article/pii/S0022227520437277

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