Integrating apaQTL and eQTL analysis identifies a potential causal variant associated with lung adenocarcinoma risk in the Chinese population

Integrating apaQTL and eQTL analysis identifies a potential causal variant associated with lung adenocarcinoma risk in the Chinese population

Abstract Alternative polyadenylation (APA) plays a crucial role in cancer biology. Here, we used data from the 3′aQTL-atlas, GTEx, and the China Nanjing Lung Cancer GWAS database to explore the association between apaQTL/eQTL-SNPs and the risk of lung adenocarcinoma (LUAD). The variant T allele of r...

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Bibliographic Details
Main Authors: Huiwen Xu, Yutong Wu, Qiong Chen, Yuhui Yu, Qianyao Meng, Na Qin, Wendi Zhang, Xiaobo Tao, Siqi Li, Tian Tian, Lei Zhang, Hongxia Ma, Jiahua Cui, Minjie Chu
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06502-0

Internet

https://doi.org/10.1038/s42003-024-06502-0

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