StackEPI: identification of cell line-specific enhancer–promoter interactions based on stacking ensemble learning

StackEPI: identification of cell line-specific enhancer–promoter interactions based on stacking ensemble learning

Abstract Background Understanding the regulatory role of enhancer–promoter interactions (EPIs) on specific gene expression in cells contributes to the understanding of gene regulation, cell differentiation, etc., and its identification has been a challenging task. On the one hand, using traditional...

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Bibliographic Details
Main Authors: Yongxian Fan, Binchao Peng
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Bioinformatics
Subjects:
Enhancer–promoter interaction
Bioinformatics
Machine learning
Stacking strategy
Feature extraction
Online Access:https://doi.org/10.1186/s12859-022-04821-9

Internet

https://doi.org/10.1186/s12859-022-04821-9

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