Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans

Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans

Growth differentiation factor-15 (GDF15) is a stress response cytokine that is elevated in several cardiometabolic diseases and has attracted interest as a potential therapeutic target. To further explore the association of GDF15 with human disease, we conducted a broad study into the phenotypic and...

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Bibliographic Details
Main Authors: Susanna Lemmelä, Eleanor M Wigmore, Christian Benner, Aki S Havulinna, Rachel MY Ong, Tibor Kempf, Kai C Wollert, Stefan Blankenberg, Tanja Zeller, James E Peters, Veikko Salomaa, Maria Fritsch, Ruth March, Aarno Palotie, Mark Daly, Adam S Butterworth, Mervi Kinnunen, Dirk S Paul, Athena Matakidou
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-08-01
Series:eLife
Subjects:
GDF15
genetics
causality
Mendelian randomisation
BMI
obesity
Online Access:https://elifesciences.org/articles/76272

Internet

https://elifesciences.org/articles/76272

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