Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses

Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses

Abstract Endothelial cells (EC) coordinate vascular homeostasis and inflammation. In organ transplantation, EC are a direct alloimmune target. We posited that tissue specific heterogeneity of vascular EC may partly underlie the disparate organ-specific alloimmune risk. We examined the vascular endot...

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Bibliographic Details
Main Authors: Hasitha Gunawardana, Tahmineh Romero, Ning Yao, Sebastiaan Heidt, Arend Mulder, David A. Elashoff, Nicole M. Valenzuela
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80102-w

Internet

https://doi.org/10.1038/s41598-020-80102-w

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