Mechanisms of ubiquitin-independent proteasomal degradation and their roles in age-related neurodegenerative disease
Neurodegenerative diseases are characterized by the progressive breakdown of neuronal structure and function and the pathological accumulation of misfolded protein aggregates and toxic protein oligomers. A major contributor to the deterioration of neuronal physiology is the disruption of protein cat...
| Main Authors: | , |
|---|---|
| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
Frontiers Media S.A.
2025-02-01
|
| סדרה: | Frontiers in Cell and Developmental Biology |
| נושאים: | |
| גישה מקוונת: | https://www.frontiersin.org/articles/10.3389/fcell.2024.1531797/full |