Phosphoproteomic investigation of targets of protein phosphatases in EGFR signaling

Abstract Receptor tyrosine kinases (RTKs) initiate cellular signaling pathways, which are regulated through a delicate balance of phosphorylation and dephosphorylation events. While many studies of RTKs have focused on downstream-activated kinases catalyzing the site-specific phosphorylation, few st...

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Bibliographic Details
Main Authors: Akihiro Eguchi, Jesper V. Olsen
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-58619-1