Circular RNA as a source of neoantigens for cancer vaccines

Background The effectiveness of somatic neoantigen-based immunotherapy is often hindered by the limited number of mutations in tumors with low to moderate mutation burden. Focusing on microsatellite-stable colorectal cancer (CRC), this study investigates the potential of tumor-associated circular RN...

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Bibliographic Details
Main Authors: Yi Ren, Bettina Lieske, Kai Yin Lee, Ker-Kan Tan, Wai-Kit Cheong, Thamizhanban Manoharan, Beijia Liu, Cyrus Zai Ming Cheng, Bei En Siew, Ian Jse-Wei Tan, Gloryn Chia
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/3/e008402.full