Modeling Human Brain Tumors and the Microenvironment Using Induced Pluripotent Stem Cells

Modeling Human Brain Tumors and the Microenvironment Using Induced Pluripotent Stem Cells

Brain cancer is a group of diverse and rapidly growing malignancies that originate in the central nervous system (CNS) and have a poor prognosis. The complexity of brain structure and function makes brain cancer modeling extremely difficult, limiting pathological studies and therapeutic developments...

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Bibliographic Details
Main Authors: Zahraa I. Khamis, Drishty B. Sarker, Yu Xue, Nancy Al-Akkary, Viviana D. James, Changchun Zeng, Yan Li, Qing-Xiang Amy Sang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
human brain cancer
induced pluripotent stem cell technology
tumor microenvironment
isogenic cells
three-dimensional (3D) cell culture models
brain organoids
Online Access:https://www.mdpi.com/2072-6694/15/4/1253

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https://www.mdpi.com/2072-6694/15/4/1253

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