Protocol to purify recombinant inflammatory caspases and assess their catalytic activity in vitro

Summary: The inflammatory caspases, such as caspase-1, caspase-4, or caspase-11, are key enzymes in mammalian innate immunity as they control inflammasome-dependent inflammation. Assessing the specific proteolytic activities of these caspases in the context of a cell remains challenging, which is wh...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Pascal Devant, Jonathan C. Kagan
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Elsevier 2022-12-01
Sraith:STAR Protocols
Ábhair:
Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S2666166722007286