Decorin–induced, preeclampsia-associated microRNA-512-3p restrains extravillous trophoblast functions by targeting USF2/PPP3R1 axis

Decorin–induced, preeclampsia-associated microRNA-512-3p restrains extravillous trophoblast functions by targeting USF2/PPP3R1 axis

Decorin (DCN) is a leucine-rich proteoglycan produced by chorionic villus mesenchymal cells anddecidual cells during human pregnancy. Studies from our laboratory demonstrated that decidua-derived DCN restrains multiple trophoblast functions including proliferation, migration, invasion andendovascula...

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Bibliographic Details
Main Authors: Chidambra D. Halari, Pinki Nandi, Jasmin Sidhu, Maria Sbirnac, Michael Zheng, Peeyush K. Lala
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
decorin
preeclampsia
microRNA
extravillous trophoblast
USF2
PPP3R1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1014672/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.1014672/full

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