Immune predisposition drives susceptibility to pneumococcal pneumonia after mild influenza A virus infection in mice

IntroductionA frequent sequela of influenza A virus (IAV) infection is secondary bacterial pneumonia. Therefore, it is clinically important to understand the genetic predisposition to IAV and bacterial coinfection.MethodsBALB/c and C57BL/6 (B6) mice were infected with high or low-pathogenic IAV and...

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Bibliographic Details
Main Authors: Sunil Palani, Md Bashir Uddin, Michael McKelvey, Shengjun Shao, Keer Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1272920/full