Restoring cellular copper homeostasis in Alzheimer disease: a novel peptide shuttle is internalized by an ATP-dependent endocytosis pathway involving Rab5- and Rab14-endosomes

CPPs, or Cell-Penetrating Peptides, offer invaluable utility in disease treatment due to their ability to transport various therapeutic molecules across cellular membranes. Their unique characteristics, such as biocompatibility and low immunogenicity, make them ideal candidates for delivering drugs,...

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Bibliographic Details
Main Authors: Michael Okafor, Olivia Champomier, Laurent Raibaut, Sebahat Ozkan, Naima El Kholti, Stéphane Ory, Sylvette Chasserot-Golaz, Stéphane Gasman, Christelle Hureau, Peter Faller, Nicolas Vitale
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1355963/full