Sex and Age Impact CD4+ T Cell Susceptibility to HIV In Vitro through Cell Activation Dynamics

Cellular composition and the responsiveness of the immune system evolve upon aging and are influenced by biological sex. CD4+ T cells from women living with HIV exhibit a decreased viral replication ex vivo compared to men’s. We, thus, hypothesized that these findings could be recapitulated in vitro...

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Bibliographic Details
Main Authors: Ludivine Brandt, Paolo Angelino, Raquel Martinez, Sara Cristinelli, Angela Ciuffi
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/23/2689