Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease.

Erythropoietin is a growth factor commonly used to manage anemia in patients with chronic kidney disease. A significant clinical challenge is relative resistance to erythropoietin, which leads to use of successively higher erythropoietin doses, failure to achieve target hemoglobin levels, and increa...

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Bibliographic Details
Main Authors: Eliyahu V Khankin, Walter P Mutter, Hector Tamez, Hai-Tao Yuan, S Ananth Karumanchi, Ravi Thadhani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2821920?pdf=render