Sleep drive reconfigures wake-promoting clock circuitry to regulate adaptive behavior.

Circadian rhythms help animals synchronize motivated behaviors to match environmental demands. Recent evidence indicates that clock neurons influence the timing of behavior by differentially altering the activity of a distributed network of downstream neurons. Downstream circuits can be remodeled by...

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Bibliographic Details
Main Authors: Markus K Klose, Paul J Shaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001324