Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis

A crucial step in cell differentiation is the silencing of developmental programs underlying multipotency. While much is known about how lineage-specific genes are activated to generate distinct cell types, the mechanisms driving suppression of stemness are far less understood. To address this, we e...

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Những tác giả chính: Debadrita Bhattacharya, Megan Rothstein, Ana Paula Azambuja, Marcos Simoes-Costa
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: eLife Sciences Publications Ltd 2018-12-01
Loạt:eLife
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Truy cập trực tuyến:https://elifesciences.org/articles/40556