Microglia and CD206+ border-associated mouse macrophages maintain their embryonic origin during Alzheimer’s disease
Brain microglia and border-associated macrophages (BAMs) display distinct spatial, developmental, and phenotypic features. Although at steady state, the origins of distinct brain macrophages are well-documented, the dynamics of their replenishment in neurodegenerative disorders remain elusive, parti...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/71879 |