Differently surface-labeled polystyrene nanoplastics at an environmentally relevant concentration induced Crohn’s ileitis-like features via triggering intestinal epithelial cell necroptosis

Differently surface-labeled polystyrene nanoplastics at an environmentally relevant concentration induced Crohn’s ileitis-like features via triggering intestinal epithelial cell necroptosis

Nanoplastics (NPs), regarded as the emerging contaminants, can enter and be mostly accumulated in the digest tract, which pose the potential threat to intestinal health. In this study, mice were orally exposed to polystyrene (PS), PS-COOH and PS-NH2 NPs with the size of ∼100 nm at a human equivalent...

Full description

Bibliographic Details
Main Authors: Dihui Xu, Yuhan Ma, Chunyan Peng, Yibin Gan, Yuheng Wang, Zining Chen, Xiaodong Han, Yabing Chen
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Environment International
Subjects:
Polystyrene nanoplastics
Crohn’s disease-like ileitis
Intestinal epithelial cells
Mitochondria
Lysosome
Autophagic flux
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412023002416

Internet

http://www.sciencedirect.com/science/article/pii/S0160412023002416

Similar Items