Thrombin-Activated Platelets Protect Vascular Endothelium against Tumor Cell Extravasation by Targeting Endothelial VCAM-1

When activated by thrombin, the platelets release their granular store of factors. These thrombin-activated platelets (TAPLT) have been shown to be capable of ameliorating pro-inflammatory processes. In this study, we tested if TAPLT could also protect the endothelium against tumor-related pro-infla...

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Bibliographic Details
Main Authors: Chiou-Mei Lee, Ming-Ling Chang, Ren-Hao Chen, Fan-Wen Chen, Jo-Chuan Liu, Shun-Li Kuo, Hsin-Hsin Peng
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/7/3433