Even Modest Prediction Accuracy of Genomic Models Can Have Large Clinical Utility

Even Modest Prediction Accuracy of Genomic Models Can Have Large Clinical Utility

Whole Genome Prediction (WGP) jointly fits thousands of SNPs into a regression model to yield estimates for the contribution of markers to the overall variance of a particular trait, and for their associations with that trait. To date, WGP has offered only modest prediction accuracy, but in some ca...

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Bibliographic Details
Main Authors: Emily Jane Dhurandhar, Ana I Vazquez, George A. Argyropoulos, David B Allison
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Genetics
Subjects:
Genomics
prediction
Statistical Genetics
methods
clinical application
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00417/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00417/full

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