Even Modest Prediction Accuracy of Genomic Models Can Have Large Clinical Utility

Whole Genome Prediction (WGP) jointly fits thousands of SNPs into a regression model to yield estimates for the contribution of markers to the overall variance of a particular trait, and for their associations with that trait. To date, WGP has offered only modest prediction accuracy, but in some ca...

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Detalhes bibliográficos
Principais autores: Emily Jane Dhurandhar, Ana I Vazquez, George A. Argyropoulos, David B Allison
Formato: Artigo
Idioma:English
Publicado em: Frontiers Media S.A. 2014-11-01
coleção:Frontiers in Genetics
Assuntos:
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00417/full