Effects of early geometric confinement on the transcriptomic profile of human cerebral organoids

Abstract Background Human cerebral organoids (hCO) are attractive systems due to their ability to model important brain regions and transcriptomics of early in vivo brain development. To date, they have been used to understand the effects of genetics and soluble factors on neurodevelopment. Interest...

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Bibliographic Details
Main Authors: Dilara Sen, Alexis Voulgaropoulos, Albert J. Keung
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12896-021-00718-2