Serum HBV RNA correlated with intrahepatic cccDNA more strongly than other HBV markers during peg-interferon treatment

Serum HBV RNA correlated with intrahepatic cccDNA more strongly than other HBV markers during peg-interferon treatment

Abstract Background Serum hepatitis B virus RNA (HBV RNA) has been reported to be a surrogate marker of intrahepatic cccDNA during nucleos(t)ide analogs therapy. However, in HBeAg-positive patients treated with peg-interferon (peg-IFN), whether HBV RNA is superior to other HBV markers in reflecting...

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Bibliographic Details
Main Authors: Xiaomei Wang, Xiumei Chi, Ruihong Wu, Hongqin Xu, Xiuzhu Gao, Lei Yu, Longgen Liu, Mingxiang Zhang, Youwen Tan, Junqi Niu, Qinglong Jin
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Virology Journal
Subjects:
Hepatitis B virus
HBV RNA
HBcrAg
HBV DNA
cccDNA
Interferon
Online Access:https://doi.org/10.1186/s12985-020-01471-2

Internet

https://doi.org/10.1186/s12985-020-01471-2

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