Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance

Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance

The hypoxic pattern of glioblastoma (GBM) is known to be a primary cause of radioresistance. Our study explored the possibility of using gene knockdown of key factors involved in the molecular response to hypoxia, to overcome GBM radioresistance. We used the U87 cell line subjected to chemical hypox...

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Bibliographic Details
Main Authors: Gaia Pucci, Luigi Minafra, Valentina Bravatà, Marco Calvaruso, Giuseppina Turturici, Francesco P. Cammarata, Gaetano Savoca, Boris Abbate, Giorgio Russo, Vincenzo Cavalieri, Giusi I. Forte
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma
radioresistance
chemical hypoxia
gene knockdown
Online Access:https://www.mdpi.com/1422-0067/25/4/2079

Internet

https://www.mdpi.com/1422-0067/25/4/2079

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