NRF3 activates mTORC1 arginine-dependently for cancer cell viability

NRF3 activates mTORC1 arginine-dependently for cancer cell viability

Summary: Cancer cells coordinate the mTORC1 signals and the related metabolic pathways to robustly and rapidly grow in response to nutrient conditions. Although a CNC-family transcription factor NRF3 promotes cancer development, the biological relevance between NRF3 function and mTORC1 signals in ca...

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Bibliographic Details
Main Authors: Shuuhei Hirose, Tsuyoshi Waku, Misato Tani, Haruka Masuda, Keiko Endo, Sanae Ashitani, Iori Aketa, Hina Kitano, Sota Nakada, Ayaka Wada, Atsushi Hatanaka, Tsuyoshi Osawa, Tomoyoshi Soga, Akira Kobayashi
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:iScience
Subjects:
Cellular physiology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223001220

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223001220

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