A functional genetic toolbox for human tissue-derived organoids
Human organoid systems recapitulate key features of organs offering platforms for modelling developmental biology and disease. Tissue-derived organoids have been widely used to study the impact of extrinsic niche factors on stem cells. However, they are rarely used to study endogenous gene function...
Main Authors: | Dawei Sun, Lewis Evans, Francesca Perrone, Vanesa Sokleva, Kyungtae Lim, Saba Rezakhani, Matthias Lutolf, Matthias Zilbauer, Emma L Rawlins |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/67886 |
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