Chronic lead exposure increases blood pressure and myocardial contractility in rats.

We investigated the cardiovascular effects of lead exposure, emphasising its direct action on myocardial contractility. Male Wistar rats were sorted randomly into two groups: control (Ct) and treatment with 100 ppm of lead (Pb) in the drinking water. Blood pressure (BP) was measured weekly. At the e...

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Bibliographic Details
Main Authors: Mirian Fioresi, Maylla Ronacher Simões, Lorena Barros Furieri, Gilson Brás Broseghini-Filho, Marcos Vinícius A Vescovi, Ivanita Stefanon, Dalton Valentim Vassallo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4026242?pdf=render