Divergent Metabolomic Signatures of TGFβ2 and TNFα in the Induction of Retinal Epithelial-Mesenchymal Transition

Divergent Metabolomic Signatures of TGFβ2 and TNFα in the Induction of Retinal Epithelial-Mesenchymal Transition

Epithelial-mesenchymal transition (EMT) is a dedifferentiation program in which polarized, differentiated epithelial cells lose their cell-cell adhesions and transform into matrix-producing mesenchymal cells. EMT of retinal pigment epithelial (RPE) cells plays a crucial role in many retinal diseases...

Full description

Bibliographic Details
Main Authors: Pei Qin Ng, Magali Saint-Geniez, Leo A. Kim, Daisy Y. Shu
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Metabolites
Subjects:
retinal pigment epithelium (RPE)
metabolomics
metabolism
mitochondria
tumor necrosis factor-alpha (TNFα)
transforming growth factor-beta (TGFβ)
Online Access:https://www.mdpi.com/2218-1989/13/2/213

Internet

https://www.mdpi.com/2218-1989/13/2/213

Similar Items