Mitochondrial Ca2+-handling in fast skeletal muscle fibers from wild type and calsequestrin-null mice.

Mitochondrial calcium handling and its relation with calcium released from sarcoplasmic reticulum (SR) in muscle tissue are subject of lively debate. In this study we aimed to clarify how the SR determines mitochondrial calcium handling using dCASQ-null mice which lack both isoforms of the major Ca(...

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Bibliographic Details
Main Authors: Michele Scorzeto, Marta Giacomello, Luana Toniolo, Marta Canato, Bert Blaauw, Cecilia Paolini, Feliciano Protasi, Carlo Reggiani, Ger J M Stienen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3789688?pdf=render