Mesenchymal stem cell-derived exosomes exert ameliorative effects in type 2 diabetes by improving hepatic glucose and lipid metabolism via enhancing autophagy

Mesenchymal stem cell-derived exosomes exert ameliorative effects in type 2 diabetes by improving hepatic glucose and lipid metabolism via enhancing autophagy

Abstract Background Mesenchymal stem cell (MSC)-based therapy is currently considered to be an effective treatment strategy for diabetes and hepatic disorders, such as liver cirrhosis and non-alcoholic fatty liver disease. Exosomes are important mediators of cellular connections, and increasing evid...

Full description

Bibliographic Details
Main Authors: Qin He, Lingshu Wang, Ruxing Zhao, Fei Yan, Sha Sha, Chen Cui, Jia Song, Huiqing Hu, Xinghong Guo, Mengmeng Yang, Yixin Cui, Yujing Sun, Zheng Sun, Fuqiang Liu, Ming Dong, Xinguo Hou, Li Chen
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Stem Cell Research & Therapy
Subjects:
Exosome
Mesenchymal stem cell
Glucose metabolism
Type 2 diabetes mellitus
Autophagy
Online Access:http://link.springer.com/article/10.1186/s13287-020-01731-6

Internet

http://link.springer.com/article/10.1186/s13287-020-01731-6

Similar Items