A draft map of the mouse pluripotent stem cell spatial proteome

The spatial location of proteins within a cell is a key element of protein function. Here the authors describe hyperLOPIT—a proteomics workflow that allows the simultaneous assignment of thousands of proteins to subcellular niches with high resolution—and apply it to mouse pluripotent stem cells....

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Bibliographic Details
Main Authors: Andy Christoforou, Claire M. Mulvey, Lisa M. Breckels, Aikaterini Geladaki, Tracey Hurrell, Penelope C. Hayward, Thomas Naake, Laurent Gatto, Rosa Viner, Alfonso Martinez Arias, Kathryn S. Lilley
Format: Article
Language:English
Published: Nature Portfolio 2016-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms9992