Rab11a is required for apical protein localisation in the intestine

Rab11a is required for apical protein localisation in the intestine

The small GTPase Rab11 plays an important role in the recycling of proteins to the plasma membrane as well as in polarised transport in epithelial cells and neurons. We generated conditional knockout mice deficient in Rab11a. Rab11a-deficient mice are embryonic lethal, and brain-specific Rab11a knoc...

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Bibliographic Details
Main Authors: Tomoaki Sobajima, Shin-ichiro Yoshimura, Tomohiko Iwano, Masataka Kunii, Masahiko Watanabe, Nur Atik, Sotaro Mushiake, Eiichi Morii, Yoshihisa Koyama, Eiji Miyoshi, Akihiro Harada
Format: Article
Language:English
Published: The Company of Biologists 2014-12-01
Series:Biology Open
Subjects:
Rab11a
Knockout mouse
Cell polarity
Brain
Intestine
Apical membrane
Online Access:http://bio.biologists.org/content/4/1/86

Internet

http://bio.biologists.org/content/4/1/86

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