High-precision mapping reveals rare N 6 -deoxyadenosine methylation in the mammalian genome

High-precision mapping reveals rare N 6 -deoxyadenosine methylation in the mammalian genome

Abstract N 6-deoxyadenosine methylation (6mA) is the most widespread type of DNA modification in prokaryotes and is also abundantly distributed in some unicellular eukaryotes. However, 6mA levels are remarkably low in mammals. The lack of a precise and comprehensive mapping method has hindered more...

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Bibliographic Details
Main Authors: Li-Qian Chen, Zhang Zhang, Hong-Xuan Chen, Jian-Fei Xi, Xue-Hong Liu, Dong-Zhao Ma, Yu-Hao Zhong, Wen Hui Ng, Tao Chen, Daniel W. Mak, Qi Chen, Yao-Qing Chen, Guan-Zheng Luo
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-022-00484-1

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https://doi.org/10.1038/s41421-022-00484-1

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