Mathematical Modelling of Intravenous Thrombolysis in Acute Ischaemic stroke: Effects of Dose Regimens on Levels of Fibrinolytic Proteins and Clot Lysis Time

Thrombolytic therapy is one of the medical procedures in the treatment of acute ischaemic stroke (AIS), whereby the tissue plasminogen activator (tPA) is intravenously administered to dissolve the obstructive blood clot. The treatment of AIS by thrombolysis can sometimes be ineffective and it can ca...

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Bibliographic Details
Main Authors: Boram Gu, Andris Piebalgs, Yu Huang, Colin Longstaff, Alun D. Hughes, Rongjun Chen, Simon A. Thom, Xiao Yun Xu
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Pharmaceutics
Subjects:
Online Access:http://www.mdpi.com/1999-4923/11/3/111