The cytotoxicity effect of 7-hydroxy-3,4-dihydrocadalene from Heterotheca inuloides and semisynthetic cadalenes derivates towards breast cancer cells: involvement of oxidative stress-mediated apoptosis
Background Heterotheca inuloides, traditionally employed in Mexico, has demonstrated anticancer activities. Although it has been proven that the cytotoxic effect is attributed to cadinane-type sesquiterpenes such as 7-hydroxy-3,4-dihydrocadalene, the mechanism of action by which these agents act in...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2023-06-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/15586.pdf |