Single-cell transcriptomics reveals shared immunosuppressive landscapes of mouse and human neuroblastoma

Background High-risk neuroblastoma is a pediatric cancer with still a dismal prognosis, despite multimodal and intensive therapies. Tumor microenvironment represents a key component of the tumor ecosystem the complexity of which has to be accurately understood to define selective targeting opportuni...

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Bibliographic Details
Main Authors: Birgit Geoerger, Aurélien Marabelle, Gaelle Pierron, Nadege Gruel, Arnaud Gauthier, Olivier Delattre, Gudrun Schleiermacher, Ana Costa, Cécile Thirant, Amira Kramdi, Cécile Pierre-Eugène, Caroline Louis-Brennetot, Orphée Blanchard, Didier Surdez, Eve Lapouble, Deborah Sitbon, Hervé Brisse, Paul Fréneaux, Mylène Bohec, Virginie Raynal, Sylvain Baulande, Renaud Leclere, Gabriel Champenois, Andre Nicolas, Didier Meseure, Angela Bellini, Fatima Mechta-Grigoriou, Laurie Menger, Isabelle Janoueix-Lerosey
Format: Article
Language:English
Published: BMJ Publishing Group 2022-08-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/8/e004807.full