Loss of the extracellular matrix glycoprotein EMILIN1 accelerates Δ16HER2-driven breast cancer initiation in mice

Loss of the extracellular matrix glycoprotein EMILIN1 accelerates Δ16HER2-driven breast cancer initiation in mice

Abstract The extracellular matrix (ECM) is an important component of the tumor microenvironment and undergoes extensive remodeling during both initiation and progression of breast cancer (BC). EMILIN1 is an ECM glycoprotein, whose function has been linked to cancer and metastasis. However, EMILIN1 r...

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Bibliographic Details
Main Authors: Andrea Favero, Ilenia Segatto, Alessandra Capuano, Maria Chiara Mattevi, Gian Luca Rampioni Vinciguerra, Lorena Musco, Sara D’Andrea, Alessandra Dall’Acqua, Chiara Gava, Tiziana Perin, Samuele Massarut, Cristina Marchini, Gustavo Baldassarre, Paola Spessotto, Barbara Belletti
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-023-00608-0

Internet

https://doi.org/10.1038/s41523-023-00608-0

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