Fluconazole Population Pharmacokinetics after Fosfluconazole Administration and Dosing Optimization in Extremely Low-Birth-Weight Infants

Fluconazole Population Pharmacokinetics after Fosfluconazole Administration and Dosing Optimization in Extremely Low-Birth-Weight Infants

ABSTRACT A prospective single-center study was conducted to characterize the pharmacokinetics (PK) of fluconazole (FLCZ) in extremely low-birth-weight infants (ELBWIs) who received fosfluconazole (F-FLCZ). Intravenous F-FLCZ was administered at a dose of 3 mg/kg of body weight every 72 h during the...

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Bibliographic Details
Main Authors: Ayano Tanzawa, Jumpei Saito, Kensuke Shoji, Yuka Kojo, Takanori Funaki, Hidehiko Maruyama, Tetsuya Isayama, Yushi Ito, Hidefumi Nakamura, Akimasa Yamatani
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
fosfluconazole
fluconazole
extremely low birth weight
infants
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01952-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.01952-21

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