Randomized double-blind personalized N-of-1 clinical trial to test the safety and potential efficacy of TJ-68 for treating muscle cramps in amyotrophic lateral sclerosis (ALS): study protocol for a TJ-68 trial

Randomized double-blind personalized N-of-1 clinical trial to test the safety and potential efficacy of TJ-68 for treating muscle cramps in amyotrophic lateral sclerosis (ALS): study protocol for a TJ-68 trial

Abstract Introduction/aims Muscle cramps are a common and often disabling symptom in amyotrophic lateral sclerosis (ALS), a devastating and incurable neurodegenerative disorder. To date, there are no medications specifically approved for the treatment of muscle cramps. Ameliorating muscle cramps in...

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Bibliographic Details
Main Authors: Hiroshi Mitsumoto, Ken Cheung, Björn Oskarsson, Howard F. Andrews, Grace E. Jang, Jinsy A. Andrews, Jaimin S. Shah, Joseph Americo Fernandes, Martin McElhiney, Regina M. Santella
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Trials
Subjects:
Kampo
TJ-68
Shakuyakukanzoto
Muscle cramps
ALS
Personalized clinical trial
Online Access:https://doi.org/10.1186/s13063-023-07424-8

Internet

https://doi.org/10.1186/s13063-023-07424-8

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