Enhancement of mucosal innate and adaptive immunity following intranasal immunization of mice with a bovine adenoviral vector

Enhancement of mucosal innate and adaptive immunity following intranasal immunization of mice with a bovine adenoviral vector

IntroductionNonhuman adenoviral (AdV) gene delivery platforms have significant value due to their ability to elude preexisting AdV vector immunity in most individuals. Previously, we have demonstrated that intranasal (IN) immunization of mice with BAd-H5HA, a bovine AdV type 3 (BAdV3) vector express...

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Bibliographic Details
Main Authors: Ekramy E. Sayedahmed, Nelly O. Elshafie, GuangJun Zhang, Sulma I. Mohammed, Suryaprakash Sambhara, Suresh K. Mittal
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
innate immunity
mucosal immunity
mucosal immunization
bovine adenoviral vector
human adenoviral vector
TLR
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1305937/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1305937/full

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