Thematic review series: Lipid Posttranslational Modifications. Geranylgeranylation of Rab GTPases

Rab GTPases require special machinery for protein prenylation, which include Rab escort protein (REP) and Rab geranylgeranyl transferase (RGGT). The current model of Rab geranylgeranylation proposes that REP binds Rab and presents it to RGGT. After geranylgeranylation of Rab C-terminal cysteines, RE...

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Bibliographic Details
Main Authors: Ka Fai Leung, Rudi Baron, Miguel C. Seabra
Format: Article
Language:English
Published: Elsevier 2006-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520336002