Mouse characteristics that affect establishing xenografts from hepatocellular carcinoma patient biopsies in the United States

Mouse characteristics that affect establishing xenografts from hepatocellular carcinoma patient biopsies in the United States

Abstract Background Hepatocellular carcinoma (HCC) patient‐derived xenograft (PDX) models hold potential to advance knowledge in HCC biology to help improve systemic therapies. Beside hepatitis B virus‐associated tumors, HCC is poorly established in PDX. Methods PDX formation from fresh HCC biopsies...

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Bibliographic Details
Main Authors: Chenhui Zou, Imane El Dika, Koen O. A. Vercauteren, Marinela Capanu, Joanne Chou, Jinru Shia, Jill Pilet, Corrine Quirk, Gadi Lalazar, Linda Andrus, Mohammad Kabbani, Amin Yaqubie, Danny Khalil, Taha Mergoub, Luis Chiriboga, Charles M. Rice, Ghassan K. Abou‐Alfa, Ype P. de Jong
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Cancer Medicine
Subjects:
Fah−/− mice
human alpha1‐antitrypsin
nitisinone
PDX
Online Access:https://doi.org/10.1002/cam4.4375

Internet

https://doi.org/10.1002/cam4.4375

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