Empagliflozin suppresses urinary mitochondrial DNA copy numbers and interleukin-1β in type 2 diabetes patients

Empagliflozin suppresses urinary mitochondrial DNA copy numbers and interleukin-1β in type 2 diabetes patients

Abstract Sodium-glucose co-transporter 2 (SGLT2) inhibitors improve cardiovascular and renal outcomes in type 2 diabetes mellitus (T2DM) patients. However, the mechanisms by which SGLT2 inhibitors improve the clinical outcomes remain elusive. We evaluated whether empagliflozin, an SGLT2 inhibitor, a...

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Bibliographic Details
Main Authors: Haekyung Lee, Hyoungnae Kim, Jin Seok Jeon, Hyunjin Noh, Rojin Park, Dong Won Byun, Hye Jeong Kim, Kyoil Suh, Hyeong Kyu Park, Soon Hyo Kwon
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22083-6

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https://doi.org/10.1038/s41598-022-22083-6

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