Independent component analysis reveals 49 independently modulated gene sets within the global transcriptional regulatory architecture of multidrug-resistant Acinetobacter baumannii

Independent component analysis reveals 49 independently modulated gene sets within the global transcriptional regulatory architecture of multidrug-resistant Acinetobacter baumannii

ABSTRACTAcinetobacter baumannii causes severe infections in humans, resists multiple antibiotics, and survives in stressful environmental conditions due to modulations of its complex transcriptional regulatory network (TRN). Unfortunately, our global understanding of the TRN in this emerging opportu...

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Bibliographic Details
Main Authors: Nitasha D. Menon, Saugat Poudel, Anand V. Sastry, Kevin Rychel, Richard Szubin, Nicholas Dillon, Hannah Tsunemoto, Yujiro Hirose, Bipin G. Nair, Geetha B. Kumar, Bernhard O. Palsson, Victor Nizet
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mSystems
Subjects:
Acinetobacter baumannii
transcriptional regulation
iModulon
Online Access:https://journals.asm.org/doi/10.1128/msystems.00606-23

Internet

https://journals.asm.org/doi/10.1128/msystems.00606-23

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