Multicellular mechanochemical hybrid cellular Potts model of tissue formation during epithelial‐mesenchymal transition

Abstract Epithelial‐mesenchymal transition (EMT) is the transdifferentiation of epithelial cells to a mesenchymal phenotype, in which cells lose epithelial‐like cell–cell adhesions and gain mesenchymal‐like enhanced contractility and mobility. EMT is crucial for tissue regeneration and is also impli...

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Bibliographic Details
Main Authors: Shreyas U. Hirway, Christopher A. Lemmon, Seth H. Weinberg
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Computational and Systems Oncology
Subjects:
Online Access:https://doi.org/10.1002/cso2.1031