Memantine protects the cultured rat hippocampal neurons treated by NMDA and amyloid β1–42

Alzheimer’s disease (AD) is a devastating neurodegenerative condition with no effective treatments. Recent research highlights the role of NMDA receptors in AD development, as excessive activation of these receptors triggers excitotoxicity. Memantine, an NMDA receptor antagonist, shows promise in cu...

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Bibliographic Details
Main Authors: Nataliia M. Rozumna, Vita V. Hanzha, Elena A. Lukyanetz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1269664/full