APC conditional knock-out mouse is a model of infantile spasms with elevated neuronal β-catenin levels, neonatal spasms, and chronic seizures
Infantile spasms (IS) are a catastrophic childhood epilepsy syndrome characterized by flexion-extension spasms during infancy that progress to chronic seizures and cognitive deficits in later life. The molecular causes of IS are poorly defined. Genetic screens of individuals with IS have identified...
Κύριοι συγγραφείς: | , , , , , , , , |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Elsevier
2017-02-01
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Σειρά: | Neurobiology of Disease |
Θέματα: | |
Διαθέσιμο Online: | http://www.sciencedirect.com/science/article/pii/S0969996116302534 |