Metabolomic profiles, polygenic risk scores and risk of rheumatoid arthritis: a population-based cohort study in the UK Biobank

Objective To investigate the relationship between metabolomic profiles, genome-wide polygenic risk scores (PRSs) and risk of rheumatoid arthritis (RA).Methods 143 nuclear magnetic resonance-based plasma metabolic biomarkers were measured among 93 800 participants in the UK Biobank. The Cox regressio...

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Bibliographic Details
Main Authors: Jie Zhang, Peng Gao, Dong-Qing Ye, Yin-Guang Fan, Quan Fang, Qing Wu, Xin-Yu Fang, Ting-Ting Qian, Su-Su Ke, Rong-Gui Huang, Heng-Chuan Zhang, Ni-Ni Qiao
Format: Article
Language:English
Published: BMJ Publishing Group 2023-10-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/9/4/e003560.full