Docetaxel-induced cognitive impairment in rats can be ameliorated by edaravone dexborneol: Evidence from the indicators of biological behavior and anisotropic fraction

Docetaxel-induced cognitive impairment in rats can be ameliorated by edaravone dexborneol: Evidence from the indicators of biological behavior and anisotropic fraction

ObjectiveThis study aimed to investigate the effect of Edaravone Dexborneol (ED) on impaired learning and memory in docetaxel (DTX)-treated rats using cognitive behavior assessments and magnetic resonance diffusion tensor imaging (DTI).Materials and methodsIn total, 24 male Sprague–Dawley rats were...

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Bibliographic Details
Main Authors: Ping Liu, Hai Liu, Lijun Wei, Xun Shi, Wei Wang, Shengxiang Yan, Wenya Zhou, Jiangong Zhang, Suxia Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Neuroscience
Subjects:
edaravone dexborneol
cognitive impairment
diffusion tensor imaging
hippocampus
fractional anisotropy
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1167425/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1167425/full

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