An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP

An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP

TCF/LEF factors are ancient context-dependent enhancer-binding proteins that are activated by β-catenin following Wnt signaling. They control embryonic development and adult stem cell compartments, and their dysregulation often causes cancer. β-catenin-dependent transcription relies on the NPF motif...

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Bibliographic Details
Main Authors: Marc Fiedler, Michael Graeb, Juliusz Mieszczanek, Trevor J Rutherford, Christopher M Johnson, Mariann Bienz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-08-01
Series:eLife
Subjects:
LIM domain-binding protein
beta-catenin
groucho/TLE
RUNX
Osa/ARID1
Wnt-responsive transcription
Online Access:https://elifesciences.org/articles/09073

Internet

https://elifesciences.org/articles/09073

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